10% Enrofloxacin Oral Solution
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Composition
100ml ine 10g Enrofloxacin
Chitarisiko
Ichi chigadzirwa chinenge chisina ruvara kune yellowish yakajeka mvura
Pharmacological chiito
Empagliflozin mushonga wakafara-spectrum bactericidal wakatsaurirwa kufluoroquinolones.Iine mhedzisiro yakanaka paEscherichia coli, Salmonella, Klebsiella, Brucella, Pasteurella, Actinobacillus pleuropneumoniae, Erysipelothrix, Proteus, Serratia marcescens, Corynebacterium pyogenes, Potter septicum, Staphylococcus aureus, Mycoplasmsacmonaseudocus, Chlamycoccus aura, Mycoplasma, Chlamycoccus Aureus, Chlamycoccus Aureus, Chlamycoccus, Chlamycoccus, Pyogene, uye Chlamycoccus. uye kushaya simba pane anaerobic bacteria.Iyo ine yakakosha post-antibacterial mhedzisiro pane inotapukira mabhakitiriya.Iyo antibacterial maitiro echiito chechigadzirwa ichi kuvharira bhakitiriya DNA gyrase, kukanganisa kudzokorodza, kunyora uye kugadzirisa uye kubatanidzwazve kwebhakitiriya DNA, uye mabhakitiriya haakwanise kukura nekuwanda zvakajairwa uye kufa.
Pharmacokinetics
Ichi chigadzirwa chinotorwa zvakanaka mushure mekutonga kwemuromo mumhuka zhinji.Iyo bioavailability yekutonga nemuromo muhuku ndeye 62.2% ~ 84%, iyo inoparadzirwa zvakanyanya muhuku uye inogona kupinda munyama uye mvura yemuviri (kusanganisira mapfupa).Kunze kwecerebrospinal fluid, huwandu hwezvinodhaka munenge matishu ese akakwirira kupfuura ari muplasma.Hepatic metabolism inonyanya kubvisa ethyl boka re7-piperazine ring kuti ribudise ciprofloxacin, rinoteverwa neoxidation uye glucuronic acid conjugation.Inonyanya kubudiswa neitsvo (ine tubular secretion uye glomerular filtration), uye 15% kusvika ku50% inobudiswa isina kuchinjwa muweti.Kubviswa kwehafu yehupenyu hwechigadzirwa ichi mushure mekutonga nemuromo muhuku ndeye 9.1 kusvika 14.2 maawa.
Kudyidzana kwezvinodhaka
(1) Ichi chigadzirwa chine synergistic mhedzisiro inosanganiswa neaminoglycosides kana yakakura-spectrum penicillin.
Heavy metal ions yakadai seCa2 +, Mg2 +, Fe3 + uye Al3 + inogona chelate nechigadzirwa ichi uye inokanganisa kutora.
(2) Kana yakashandiswa pamwe chete netheophylline uye caffeine, iyo plasma protein binding rate inogona kuderedzwa, iyo yakadzika ye theophylline uye caffeine inogona kuwedzera zvakanyanya, uye kunyange zviratidzo zveophylline chepfu zvinogona kuitika.
(3) Ichi chigadzirwa chine mhedzisiro yekuvharisa hepatic drug enzymes, iyo inogona kuderedza chiyero chemvumo chemishonga inonyanya kushandiswa muchiropa uye kuwedzera plasma concentration.
(4) Chiito uye kushandiswa: Fluoroquinolone antibacterial zvinodhaka.Inoshandiswa kune zvirwere zvebhakitiriya uye mycoplasma utachiona muhuku.
Dosage uye kutonga
Chinwiwa chakasanganiswa: 0.5 ~ 0.75 ml yehuku pa1 L yemvura.
Maitiro asina kunaka
(1) Kupera kweshwashwa kunoitika mumhuka duku, kuchikanganisa kukura kwemapfupa uye kuchikonzera kukamhina uye kurwadziwa.
(2) Digestive system reactions inosanganisira kurasikirwa nechido, manyoka, nezvimwe.
Zvekungwaririra
Inopikiswa pakukandira huku panguva yekukandira
Nguva yekubvisa
Avian: 8 mazuva
Storage
Yakavharwa uye yakachengetwa, yakachengetedzwa kubva kuchiedza.
Hebei Veyong Pharmaceutical Co., Ltd, yakavambwa muna 2002, iri muShijiazhuang City, Hebei Province, China, padyo neguta guru Beijing.Iye ihombe GMP-yakasimbiswa veterinary drug bhizinesi, ine R&D, kugadzira uye kutengesa kweVeterinary APIs, gadziriro, premixed feed uye feed additives.SeProvincial Technical Center, Veyong yakamisa hurongwa hweR&D hwemishonga mitsva yezvipfuyo, uye ndiyo inozivikanwa pasi rose tekinoroji innovation yakavakirwa bhizinesi rezvipfuyo, kune makumi matanhatu neshanu nyanzvi.Veyong ine mabhesi maviri ekugadzira: Shijiazhuang neOrdos, iyo iyo Shijiazhuang base inovhara nzvimbo ye78,706 m2, ine 13 API zvigadzirwa zvinosanganisira Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, uye 11, gadziriro yekugadzira oral poda, mitsara yekugadzira oral. , premix, bolus, mishonga yezvipembenene nemishonga inouraya utachiona, ects.Veyong inopa APIs, anopfuura zana ega- label gadziriro, uye OEM & ODM sevhisi.
Veyong inokoshesa zvikuru manejimendi eEHS(Environment, Health & Safety) system, uye yakawana ISO14001 uye OHSAS18001 zvitupa.Veyong yakanyorwa mumabhizinesi ari kusimukira maindasitiri muHebei Province uye inogona kuve nechokwadi chekuenderera mberi kwezvigadzirwa.
Veyong yakamisa hurongwa hwekutonga kwemhando yakakwana, yakawana chitupa cheISO9001, chitupa cheChina GMP, chitupa cheAustralia APVMA GMP, chitupa cheEthiopia GMP, chitupa cheIvermectin CEP, uye yakapasa ongororo yeUS FDA.Veyong ine timu yehunyanzvi yekunyoresa, kutengesa uye tekinoroji sevhisi, kambani yedu yakawana kuvimba nerutsigiro kubva kune akawanda vatengi nemhando yepamusoro yechigadzirwa, yepamusoro-yemhando yepamusoro-yekutanga kutengesa uye mushure mekutengesa sevhisi, yakakomba uye yesainzi manejimendi.Veyong yaita kushandira pamwe kwenguva refu nemabhizinesi mazhinji anozivikanwa pasi rose emishonga yemhuka ane zvigadzirwa zvinotengeswa kuEurope, South America, Middle East, Africa, Asia, etc. kupfuura nyika makumi matanhatu nematunhu.
