Ivermectin

Tsanangudzo Pfupi

CAS nhamba: 70288-86-7

Molecular formula: C48H74O14

Chiratidzo: Antibiotic anti-parasitic drug

Zvitupa: EU COS, US FDA, GMP, ISO9001

Tsanangudzo: EP, BP, USP

Zviri mukati: ≥96%

Zvakanakira: Kusachena kwakaderera

Muenzaniso: Inowanikwa

Kurongedza: 1kg / aluminium bag.

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Ivermectin

Ivermectinupfu huchena hwecrystalline, husina hwema.Inonyungudika zvakasununguka mumethanol, ethanol, acetone, ethyl acetate, isinganyunguriki mumvura, uye zvishoma hygroscopic.Ivermectin is semisynthetic macrolide multi-component antibiotic, iyo inonyanya kuve ne ivermectin B1 (Bla + B1b) yemukati isingasviki 95%, iyo Bla yemukati isiri pasi pe85%.

Nheyo Yomushonga

Ivermectin ine yakasarudzika inhibitory mhedzisiro, nekusunga kune yakakwira hukama hwechloride migero ine glutamate sevharuvhu mumasero etsinga uye tsandanyama masero emhuka dzisina spinless, izvo zvinotungamira mukuwedzera kwepermeability ye cell membranes kune chloride ion, inokonzera hyperpolarization yemasero etsinga. kana masero emhasuru, uye zvinokonzera kuoma mitezo kana kufa kwezvipembenene.Iyo zvakare inopindirana ne chloride migero yemamwe ligand mavharuvhu, akadai neurotransmitter g-aminobutyric acid (GABA).Kusarudzwa kwechigadzirwa ichi imhaka yekuti dzimwe mhuka dzinoyamwisa hadzina glutamate-chloride migero mu vivo, uye avermectin inongova nehukama hwakaderera hwemammalian ligand-chloride migero.Ichi chigadzirwa hachigone kupinda muropa remunhu-uropi chipingamupinyi.Onchocerciasis uye strongyloidiasis uye hookworm, ascaris, Trichuris trichiura, uye Enterobius vermicularis zvirwere.

Kushandisa

Ivermectin mushonga unoshandiswa kurapa marudzi mazhinji emaparasite infestations.Ivermectin inoshandiswa kurapa mhuka zvirwere zvinokonzerwa neroundworms uye ectoparasites.

Ivermectin inogara ichishandiswa kudzora honye dzeparasitic mudumbu remhuka dzinotyisa.Zvipembenene izvi zvinowanzopinda mumhuka kana ichifura, ichipfuura ura, uye kuisa uye kukura muura, mushure mezvo zvinobudisa mazai anosiya mhuka kuburikidza nemarara ayo uye anogona kukanganisa mafuro matsva.Ivermectin inoshanda mukuuraya mamwe, asi kwete ese, ezvipembenene izvi.Mumbwa inogara ichishandiswa seprophylaxis kurwisa heartworm.

Mukurapa kwezvipfuyo, inoshandiswa kudzivirira nekurapa heartworm uye acariasis, pakati pezvimwe zviratidzo.Inogona kutorwa nemuromo kana kushandiswa paganda rekunze kwekunze.Ivermectin inoshandiswa zvakanyanya kuita gastrointestinal nematodes, lungworms, uye parasitic arthropods mumombe, makwai, mabhiza, uye nguruve, intestinal nematodes mumbwa, ear mites, Sarcoptes scabiei, heart filariae, uye microfilariae, uye gastrointestinal nematodes nematodes.