Tiamulin hydrogen fumarate

Tsananguro Pfupi:

CAS nhamba:55297-96-6

Molecular fomura: C32H51NO8S


Chigadzirwa Chigadzirwa

Chigadzirwa Mateki

Tiamulin hydrogen fumarate

Tiamulin hydrogen fumarate is a derivative of pleuromutilin, inogona kushandiswa mumushonga wezvipfuyo kunyanya yenguruve nehuku.Iyo diterpene antimicrobial ine pleuromutilin kemikari chimiro yakafanana neiyo yevalnemulin.

Tiamulin hydrogen fumarate yakachena kana ingangoita chena poda yemucheka, isina hwema uye isinganake. Inonyungudika nyore nyore mu methanol kana ethanol, inosungunuka mumvura, yakanyungudika zvishoma muacetone, uye ingango nyungudika mu hexane.

Tiamulin-Hydrogen-Fumarate1

Mamiriro ekuita uye hunhu

Ichi chigadzirwa ibhakitiriya bacteriostatic, asi zvakare ine bactericidal maitiro pane anonzwisisa mabhakitiriya pakakwirira zvakanyanya. Iyo inorwisa mabhakitiriya mashandiro ekuita ndeyekudzivirira bhakitiriya mapuroteni synthesis nekusunga kune iyo 50s subunit yebhakitiriya ribosome.

Tiamulin hydrogen fumarate ine yakanaka inorwisa mabhakitiriya kurwisa dzakasiyana siyana dzeGram-yakanaka cocci, inosanganisira yakawanda staphylococci uye streptococci (kunze kweboka D streptococci) uye akasiyana siyana emycoplasmas uye mamwe ma spirochetes. Nekudaro, iyo antibacterial chiitiko kune mamwe mabhakitiriya asina kusimba haina kusimba, kunze kwemhando dzeHaemophilus uye mamwe E. coli neKlebsiella strains.

Tiamulin hydrogen fumarate iri nyore kupinza mushure mekutaurwa kwemuromo munguruve. Inenge 85% yedhizaini imwe inosvirwa, uye kukwirisa kwepamusoro kunoitika mumaawa maviri kusvika mana. Inoparadzirwa kwazvo mumuviri, iine yakanyanya kusangana mumapapu. Tiamulin hydrogen fumarate inogadziriswa mumuviri kuita makumi maviri emetabolite, mamwe aine runyararo rwekurwisa mabhakitiriya. Inenge makumi matatu kubva muzana emametabolite anoburitswa mumuti uye zvakasara zvinoburitswa mutsvina.

Kushandisa

Tiamulin hydrogen fumarate inoshandiswa pakurapa nguruve pneumonia inokonzerwa neActinobacillus pleuropneumoniae uye nguruve yeropa dysentery inokonzerwa neTreponema hyodysenteriae. Sekudya chinodhaka chinowedzera chenguruve chinogona kusimudzira huremu Izvo zvinoshandawo pakurwisa chirwere chisingaperi chekufema muhuku, mycoplasma hyopneumonia, uye staphylococcal synovitis muhuku.

Zvemukati

≥ 98%

Tsanangudzo

USP42 / EP10

Kurongedza

25kg / kadhibhodhi dhiramu

Kugadzirira

10%, 45% 80% Tiamulin hydrogen fumarate premix / yakasviba poda


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