20% Florfenicol WSP
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Vhidhiyo
Pharmacodynamics
Florfenicol i-broad-spectrum amide alcohol antibiotic uye bacteriostatic agent, iyo inoshanda nekudzivisa kuumbwa kwemapuroteni ebhakitiriya nekusunga kune 50S subunit ye ribosome.Iine simba rinorwisa mabhakitiriya rinopikisa zvakasiyana-siyana zve gram-positive uye gram-negative mabhakitiriya.Pasteurella hemolytica, Pasteurella multocida, uye Actinobacillus pleuropneumoniae anobatwa zvakanyanya neflorfenicol.Basa reantibacterial reflorfenicol kurwisa tupukanana twakawanda mu vitro rakafanana kana kusimba kupfuura iro rethiamphenicol, uye mamwe mabhakitiriya anoshingirira kune amide alcohols nekuda kweacetylation, senge Escherichia coli neKlebsiella pneumoniae, anogona kunge achiri Sensitive kune florfenicol.
Inonyanya kushandiswa kune zvirwere zvebhakitiriya zvenguruve, huku nehove zvinokonzerwa nehutachiona hwehutachiona, zvakadai sezvirwere zvekufema zvemombe nenguruve zvinokonzerwa nePasteurella hemolytica, Pasteurella multocida uye Actinobacillus pleuropneumoniae.Chirwere chetyphoid uye chirwere cheparatyphoid chinokonzerwa neSalmonella, chicken cholera, pullorum, Escherichia coli, nezvimwewo;mabhakitiriya ehove anokonzerwa nePasteurella, Vibrio, Staphylococcus aureus, Hydromonas, Enteritidis, etc. Sepsis, enteritis, chirwere chitsvuku cheganda, nezvimwewo.
Pharmacokinetics
Oral administration ye florfenicol inokurumidza kunyura, uye kurapa kwehutano kunogona kusvika muropa mushure meawa imwe chete, uye huwandu hwepamusoro hweropa hunogona kusvika mumaawa 1 kusvika ku3.Iyo bioavailability inopfuura 80%.Florfenicol inoparadzirwa zvakanyanya mumhuka uye inogona kupfuura nemuropa-brain barriers.Inonyanya kubudiswa mumhando yepakutanga kubva muweti, uye chiduku chiduku chinobudiswa netsvina.
Kudyidzana kwezvinodhaka
(1) Macrolides uye lincosamides vane chinangwa chimwe chekuita sechigadzirwa ichi, zvose zvakasungwa kune 50S subunit yebhakteria ribosome, uye inogona kuunza kupesana kwepakati kana yakashandiswa pamwe chete.(2) Inogona kupikisa bactericidal basa repenicillin kana aminoglycosides, asi haina kuratidzwa mumhuka.
Chiito uye kushandiswa
Amide doro remishonga inorwisa mabhakitiriya.Kune Pasteurella uye Escherichia coli zvirwere.
Kushandisa uye Dosage
Kubva pachigadzirwa ichi.Oral administration: pa1kg uremu hwemuviri, 0.1 ~ 0.15g yenguruve nehuku.2 kanomwe pazuva kwemazuva matatu kusvika mashanu.Hove 50 ~ 75mg.1 nguva pazuva kwemazuva matatu kusvika mashanu.
Maitiro asina kunaka
20% Florfenicol mvura yakasvibiswa poda ine imwe immunosuppressive effect kana yakashandiswa pachiyero chepamusoro pane chirongwa chinokurudzirwa.
Attention
(1) Huku dzinokandira mazai kuti dzidyiwe nevanhu hadzifaniri kushandiswa panguva yokukandira mazai;(2) Shandisa nekuchenjerera muvaridzi.Iine embryotoxicity uye inofanira kushandiswa nekuchenjerera muzvipfuwo zvine pamuviri uye zvinoyamwisa;(3) Inopikiswa panguva yekudzivirira kana mumhuka dzine immunodeficiency yakasimba;(4) Mumhuka dzine renal insufficiency, dose inofanira kuderedzwa zvakakodzera kana kuti nguva yekutora inofanira kuwedzerwa.
Nguva yekubvisa
Mazuva makumi maviri enguruve, mazuva mashanu ehuku;375 madhigirii mazuva ehove.
Storage
Ramba wakavharwa uye munzvimbo yakaoma
Hebei Veyong Pharmaceutical Co., Ltd, yakavambwa muna 2002, iri muShijiazhuang City, Hebei Province, China, padyo neguta guru Beijing.Iye ihombe GMP-yakasimbiswa veterinary drug bhizinesi, ine R&D, kugadzira uye kutengesa kweVeterinary APIs, gadziriro, premixed feed uye feed additives.SeProvincial Technical Center, Veyong yakamisa hurongwa hweR&D hwemishonga mitsva yezvipfuyo, uye ndiyo inozivikanwa pasi rose tekinoroji innovation yakavakirwa bhizinesi rezvipfuyo, kune makumi matanhatu neshanu nyanzvi.Veyong ine mabhesi maviri ekugadzira: Shijiazhuang neOrdos, iyo iyo Shijiazhuang base inovhara nzvimbo ye78,706 m2, ine 13 API zvigadzirwa zvinosanganisira Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, uye 11, gadziriro yekugadzira oral poda, mitsara yekugadzira oral. , premix, bolus, mishonga yezvipembenene nemishonga inouraya utachiona, ects.Veyong inopa APIs, anopfuura zana ega- label gadziriro, uye OEM & ODM sevhisi.
Veyong inokoshesa zvikuru manejimendi eEHS(Environment, Health & Safety) system, uye yakawana ISO14001 uye OHSAS18001 zvitupa.Veyong yakanyorwa mumabhizinesi ari kusimukira maindasitiri muHebei Province uye inogona kuve nechokwadi chekuenderera mberi kwezvigadzirwa.
Veyong yakamisa hurongwa hwekutonga kwemhando yakakwana, yakawana chitupa cheISO9001, chitupa cheChina GMP, chitupa cheAustralia APVMA GMP, chitupa cheEthiopia GMP, chitupa cheIvermectin CEP, uye yakapasa ongororo yeUS FDA.Veyong ine timu yehunyanzvi yekunyoresa, kutengesa uye tekinoroji sevhisi, kambani yedu yakawana kuvimba nerutsigiro kubva kune akawanda vatengi nemhando yepamusoro yechigadzirwa, yepamusoro-yemhando yepamusoro-yekutanga kutengesa uye mushure mekutengesa sevhisi, yakakomba uye yesainzi manejimendi.Veyong yaita kushandira pamwe kwenguva refu nemabhizinesi mazhinji anozivikanwa pasi rose emishonga yemhuka ane zvigadzirwa zvinotengeswa kuEurope, South America, Middle East, Africa, Asia, etc. kupfuura nyika makumi matanhatu nematunhu.
