20% Albendazole Granule
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Pharmacology
Albendazole inogadzirwa nebenzimidazole, inogona kukurumidza kugadzirwa mumuviri kuita sulfoxide, sulfone doro uye 2-aminosulfone doro.Iyo inosarudza uye isingadzoreki inodzivirira iyo polymerization ye cytoplasmic microtubule system yeparasite ye intestinal wall maseru kune intestinal nematodes, iyo inogona kuvharira kutora uye kutorwa kwezvakasiyana-siyana zvekudya uye glucose, zvichiita kuneta kune endogenous glycogen muzvipembenene, uye inhibits. fumarate reductase Iyo sisitimu inodzivirira kugadzirwa kweadenosine triphosphate uye inotadzisa kurarama uye kuberekana kwehonye.Zvakafanana nemebendazole, chigadzirwa ichi chinogonawo kukonzera kuderera kwe cytoplasmic microtubules ye intestinal masero ehonye, uye kusunga kune tubulin yayo, zvichiita kuti intracellular transportation ivharwe, zvichiita kuti Golgi endocrine granules iunganidzwe, cytoplasmic zvishoma nezvishoma kupera, uye kupera kwakakwana kwekunyura. masero.Zvinokonzera kufa kwegonye.20% Albendazole granuleinogona kuuraya zvachose mazai ehookworm uye mazai ewhipworm uye pamwe kuuraya mazai eroundworm.Pamusoro pekuuraya nekudzinga akasiyana nematodes ayo ari parasitic mumhuka, zvakare ine kuuraya kuri pachena uye kudzinga mhedzisiro patapeworms uye cysticercus.
Toxicology
Toxicological bvunzo dzinoratidza kuti chigadzirwa ichi chine yakaderera chepfu uye chakachengeteka.Iyo yemuromo LD50 yemakonzo yakakura kupfuura 800mg/kg, uye iyo yakanyanya kushivirira dose yembwa inodarika 400mg/kg.Mushonga uyu hauna mhedzisiro pabasa rekuzvara mbeva dzechirume, uye hauna teratogenic mhedzisiro pamakonzo echikadzi.Kusvetwa kweFetal kunogona kuitika kana muyero mukuru [30 mg/(㎏·day)] ukaiswa kumakonzo echikadzi netsuro hadzi.Uye skeletal deformities.
Kushandisa uye Dosage
Kubva pane albendazole.Oral administration: kamwe chete, 25 ~ 50mg / kg uremu hwemuviri.Kana kuti tevera mazano achiremba.
Zvakaipa Zvinoita
(1) imbwa padzakapiwa 50 mg/kg kaviri pazuva, zvishoma nezvishoma dzaizotanga kuita anorexia
(2) Kushandiswa kweAlbendazole mukutanga pamuviri kunogona kuperekedzwa ne teratogenicity uye embryotoxicity.
Cherechedza
Mhuka dzinofanira kungwarira mumazuva makumi mana nemashanu ekutanga mushure mekuita pamuviri
Hebei Veyong Pharmaceutical Co., Ltd, yakavambwa muna 2002, iri muShijiazhuang City, Hebei Province, China, padyo neguta guru Beijing.Iye ihombe GMP-yakasimbiswa veterinary drug bhizinesi, ine R&D, kugadzira uye kutengesa kweVeterinary APIs, gadziriro, premixed feed uye feed additives.SeProvincial Technical Center, Veyong yakamisa hurongwa hweR&D hwemishonga mitsva yezvipfuyo, uye ndiyo inozivikanwa pasi rose tekinoroji innovation yakavakirwa bhizinesi rezvipfuyo, kune makumi matanhatu neshanu nyanzvi.Veyong ine mabhesi maviri ekugadzira: Shijiazhuang neOrdos, iyo iyo Shijiazhuang base inovhara nzvimbo ye78,706 m2, ine 13 API zvigadzirwa zvinosanganisira Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, uye 11, gadziriro yekugadzira oral poda, mitsara yekugadzira oral. , premix, bolus, mishonga yezvipembenene nemishonga inouraya utachiona, ects.Veyong inopa APIs, anopfuura zana ega- label gadziriro, uye OEM & ODM sevhisi.
Veyong inokoshesa zvikuru manejimendi eEHS(Environment, Health & Safety) system, uye yakawana ISO14001 uye OHSAS18001 zvitupa.Veyong yakanyorwa mumabhizinesi ari kusimukira maindasitiri muHebei Province uye inogona kuve nechokwadi chekuenderera mberi kwezvigadzirwa.
Veyong yakamisa hurongwa hwekutonga kwemhando yakakwana, yakawana chitupa cheISO9001, chitupa cheChina GMP, chitupa cheAustralia APVMA GMP, chitupa cheEthiopia GMP, chitupa cheIvermectin CEP, uye yakapasa ongororo yeUS FDA.Veyong ine timu yehunyanzvi yekunyoresa, kutengesa uye tekinoroji sevhisi, kambani yedu yakawana kuvimba nerutsigiro kubva kune akawanda vatengi nemhando yepamusoro yechigadzirwa, yepamusoro-yemhando yepamusoro-yekutanga kutengesa uye mushure mekutengesa sevhisi, yakakomba uye yesainzi manejimendi.Veyong yaita kushandira pamwe kwenguva refu nemabhizinesi mazhinji anozivikanwa pasi rose emishonga yemhuka ane zvigadzirwa zvinotengeswa kuEurope, South America, Middle East, Africa, Asia, etc. kupfuura nyika makumi matanhatu nematunhu.
