Benzypencillin sodium poda yejekiseni
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Pharmacological chiito
Pharmacological chiito
Penicillin mushonga unorwisa mabhakitiriya une simba rinorwisa mabhakitiriya, uye maitiro ayo anorwisa mabhakitiriya ari kunyanya kuvharidzira kuumbwa kwebhakitiriya sero rusvingo mucopeptides.Sensitive mabhakitiriya ari padanho rekukura anopatsanura zvine simba, uye sero madziro ari mubiosynthesis nhanho.Pasi pekuita kwepenicillin, kuumbwa kwemucopeptides kwakavharwa uye rusvingo rwesero harugone kuumbwa, uye membrane yesero inoputika uye inofa pasi pechiito cheosmotic pressure.
Penicillin inorwisa mabhakitiriya ane nhete-spectrum, kunyanya inorwisa mabhakitiriya akasiyana-siyana eGram-positive uye nhamba shoma yeGram-negative cocci.Mabhakitiriya makuru anonzwa ndiwo Staphylococcus, Streptococcus, Erysipelas suis, Corynebacterium, Clostridium tetani, Actinomycetes, Bacillus anthracis, Spirochetes, etc. Isinganzwisisi kune mycobacteria, mycoplasma, chlamydia, rickettsia, nocardia, fungi uye mavhairasi.
Pharmacological chiito
Pharmacokinetics
Mushure mejekiseni remukati memuscular repenicillin, procaine inotorwa zvishoma nezvishoma mushure mekuburitswa kwepenicillin nemuno hydrolysis.Nguva yepamusoro yakareba uye huwandu hweropa hwakaderera, asi mhedzisiro yacho yakareba kupfuura iyo yepenicillin.Inongogumira kune mabhakitiriya epathogenic ane hanya zvakanyanya nepenicillin, uye haifanirwe kushandiswa kurapa hutachiona hwakakomba.Mushure mekunge procaine penicillin uye penicillin sodium (potassium) yasanganiswa uye yakagadzirwa majekiseni, kuwanda kweropa kwemushonga kunogona kuwedzerwa munguva pfupi, kuitira kupa kufunga kune zvose-refu-kuita uye nekukurumidza-kuita.Jekiseni guru reprocaine penicillin rinogona kukonzera chepfu yeprocaine.
Kudyidzana Kwezvinodhaka
(1) Iko kusanganiswa kwepenicillin uye aminoglycosides kunogona kuwedzera kuwanda kweiyo yekupedzisira mubhakitiriya, saka inopa synergistic mhedzisiro.
(2) Kukurumidza-kuita bacteriostatic agents zvakadai semacrolides, tetracyclines uye amide alcohols zvinokanganisa basa rebhakitiriya repenicillin uye haifaniri kushandiswa pamwe chete.
(3) Heavy metal ions (kunyanya mhangura, zingi, mercury), doro, asidhi, ayodhini, oxidizing agents, zvinoderedza, hydroxyl compounds, acidic glucose jekiseni kana tetracycline hydrochloride jekiseni inogona kuparadza basa repenicillin uye inoenderana Taboo.
(4) Haifanirwe kusanganiswa nemimwe mishonga inogadzirisa (senge chlorpromazine hydrochloride, lincomycin hydrochloride, norepinephrine tartrate, oxytetracycline hydrochloride, tetracycline hydrochloride, B mavhitaminzi uye vhitamini C), zvikasadaro turbidity, flocculent solids kana mvura inonaya.
Zviratidzo
Inonyanya kushandiswa kwezvirwere zvisingaperi zvinokonzerwa nepenicillin-sensitive bacteria, senge bovine pyometra, mastitis, yakaoma fractures, nezvimwewo, uyewo kune zvirwere zvakadai se actinomycetes uye leptospirosis.
Kushandisa uye Dosage
Wedzera mvura isina utachiona yejekiseni kugadzira musanganiswa usati washandisa.Intramuscular jekiseni: Mushonga mumwe, pa1kg uremu hwemuviri, 10,000 kusvika 20,000 mayuniti emabhiza nemombe;20,000 kusvika ku30,000 mayuniti emakwai, nguruve, nehadzi;30,000 kusvika 40,000 zvikamu zvembwa nekatsi.1 nguva pazuva kwemazuva 2-3.
Maitiro asina kunaka
(1) Kunyanya kusawirirana, izvo zvinogona kuitika muzvipfuyo zvakawanda, asi chiitiko chakaderera.Mhedzisiro yemunharaunda inoratidzwa semvura uye kurwadziwa panzvimbo yejekiseni, uye systemic reaction ndeye gwirikwiti uye kuputika, izvo zvinogona kukonzera kuvhunduka kana kufa mumamiriro ezvinhu akaoma.
(2) Mune dzimwe mhuka, hutachiona hwepamuviri hunogona kukonzerwa.
Zvekungwaririra
(1) Chigadzirwa ichi chinoshandiswa kurapa zvirwere zvisingaperi zvinokonzerwa nehutachiona hwehutachiona.
(2) Kunyungudika zvishoma mumvura.Muchiitiko cheasidhi, alkali kana oxidizing agent, ichakundikana nokukurumidza.Nokudaro, jekiseni rinofanira kugadzirirwa nguva isati yashandiswa.
(3) Ngwarira kupindirana uye kusapindirana nemamwe madhiragi, kuitira kuti usakanganisa kushanda kwemushonga.
Nguva yekubvisa
mombe, makwai nenguruve mazuva makumi maviri namasere;Maawa makumi manomwe nemaviri ekusiya mukaka
Hebei Veyong Pharmaceutical Co., Ltd, yakavambwa muna 2002, iri muShijiazhuang City, Hebei Province, China, padyo neguta guru Beijing.Iye ihombe GMP-yakasimbiswa veterinary drug bhizinesi, ine R&D, kugadzira uye kutengesa kweVeterinary APIs, gadziriro, premixed feed uye feed additives.SeProvincial Technical Center, Veyong yakamisa hurongwa hweR&D hwemishonga mitsva yezvipfuyo, uye ndiyo inozivikanwa pasi rose tekinoroji innovation yakavakirwa bhizinesi rezvipfuyo, kune makumi matanhatu neshanu nyanzvi.Veyong ine mabhesi maviri ekugadzira: Shijiazhuang neOrdos, iyo iyo Shijiazhuang base inovhara nzvimbo ye78,706 m2, ine 13 API zvigadzirwa zvinosanganisira Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, uye 11, gadziriro yekugadzira oral poda, mitsara yekugadzira oral. , premix, bolus, mishonga yezvipembenene nemishonga inouraya utachiona, ects.Veyong inopa APIs, anopfuura zana ega- label gadziriro, uye OEM & ODM sevhisi.
Veyong inokoshesa zvikuru manejimendi eEHS(Environment, Health & Safety) system, uye yakawana ISO14001 uye OHSAS18001 zvitupa.Veyong yakanyorwa mumabhizinesi ari kusimukira maindasitiri muHebei Province uye inogona kuve nechokwadi chekuenderera mberi kwezvigadzirwa.
Veyong yakamisa hurongwa hwekutonga kwemhando yakakwana, yakawana chitupa cheISO9001, chitupa cheChina GMP, chitupa cheAustralia APVMA GMP, chitupa cheEthiopia GMP, chitupa cheIvermectin CEP, uye yakapasa ongororo yeUS FDA.Veyong ine timu yehunyanzvi yekunyoresa, kutengesa uye tekinoroji sevhisi, kambani yedu yakawana kuvimba nerutsigiro kubva kune akawanda vatengi nemhando yepamusoro yechigadzirwa, yepamusoro-yemhando yepamusoro-yekutanga kutengesa uye mushure mekutengesa sevhisi, yakakomba uye yesainzi manejimendi.Veyong yaita kushandira pamwe kwenguva refu nemabhizinesi mazhinji anozivikanwa pasi rose emishonga yemhuka ane zvigadzirwa zvinotengeswa kuEurope, South America, Middle East, Africa, Asia, etc. kupfuura nyika makumi matanhatu nematunhu.
