30% Florfenicol Jekiseni
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Pharmacological Action
Florfenicol ndeye yakakura-spectrum inorwisa mabhakitiriya yeamide doro uye bacteriostatic agent.Inoshanda nekusunga kune 50S subunit yeribosome kuti inhibisa kuumbwa kweprotein yebhakitiriya.Iine simba rinorwisa mabhakitiriya rinopikisa zvakasiyana-siyana zve gram-positive uye gram-negative mabhakitiriya.Pasteurella hemolyticus, Pasteurella multocida uye Actinobacillus pleuropneumoniae vanonzwa zvakanyanya neflorfenicol.Iyo antibacterial chiitiko cheflorfenicol kurwisa tupukanana twakawanda mu vitro yakafanana kana yakasimba kupfuura iyo yethiamphenicol.Mamwe mabhakitiriya anopokana neamide alcohols nekuda kweacetylation, senge Escherichia coli neKlebsiella pneumoniae, anogona kunge achiri kurwisa fluorobenzene.Nico arikunzwa.Inonyanya kushandiswa kuzvirwere zvebhakitiriya zvenguruve, huku nehove zvinokonzerwa nehutachiona hwehutachiona, zvakadai sezvirwere zvekufema zvemombe nenguruve zvinokonzerwa nePasteurella hemolyticus, Pasteurella multocida uye Actinobacillus pleuropneumoniae.Salmonella inokonzerwa nefivha yetyphoid uye paratyphoid fever, chicken cholera, chicken pullorum, colibacillosis, nezvimwewo;hove bhakitiriya sepsis inokonzerwa nehove pasteurella, vibrio, Staphylococcus aureus, hydrophila, enteritidis, etc. Enteritis, chirwere cheganda chitsvuku, nezvimwewo.
Pharmacokinetics
Florfenicol inokurumidza kubatwa nemuromo wekutonga, uye iyo yekurapa kusungirirwa inogona kusvikwa muropa mushure meawa imwe, uye iyo yepamusoro yeropa inogona kusvika mukati me1 kusvika maawa matatu.Iyo bioavailability inopfuura 80%.Florfenicol inoparadzirwa zvakanyanya mumhuka uye inogona kupinda muropa-brain barriers.Inonyanya kubudiswa muweti muchimiro chayo chepakutanga, uye chiduku chiduku chinobudiswa mumarara.
Chiito uye Kushandisa
Amidol antibiotics.KuPasteurella neE. coli zvirwere.
Dosage uye Administration
Intramuscular jekiseni: mushonga mumwe chete, 0.067 ml yehuku uye 0.05 ~ 0.067 ml yenguruve pa1 kg uremu hwemuviri.Ese kwemaawa makumi mana nemasere e2 dosi.Hove 0.0017 ~ 0.0034ml, qd.
Zvakaipa Zvinoita
1.30% Florfenicol jekiseniine imwe immunosuppressive mhedzisiro kana ichishandiswa pamadosi akakwira kupfuura inokurudzirwa dosi.
2. Iine embryotoxicity uye inofanira kushandiswa nekuchenjerera muzvipfuwo panguva yekuzvitakura uye lactation.
Zvekungwaririra:
1. Inopikiswa pakukandira huku panguva yekukandira.
2. Inopikiswa panguva yekudzivirira kana mumhuka dzine hutachiona hwakanyanya kukanganisa.
3. Kuderedza dose kwakakodzera kana kurebesa nguva yedosing inodiwa mumhuka dzakabatwa dzine renal insufficiency.
Withdrawal Period
Nguruve mazuva gumi nemana, huku 28 mazuva.
Hebei Veyong Pharmaceutical Co., Ltd, yakavambwa muna 2002, iri muShijiazhuang City, Hebei Province, China, padyo neguta guru Beijing.Iye ihombe GMP-yakasimbiswa veterinary drug bhizinesi, ine R&D, kugadzira uye kutengesa kweVeterinary APIs, gadziriro, premixed feed uye feed additives.SeProvincial Technical Center, Veyong yakamisa hurongwa hweR&D hwemishonga mitsva yezvipfuyo, uye ndiyo inozivikanwa pasi rose tekinoroji innovation yakavakirwa bhizinesi rezvipfuyo, kune makumi matanhatu neshanu nyanzvi.Veyong ine mabhesi maviri ekugadzira: Shijiazhuang neOrdos, iyo iyo Shijiazhuang base inovhara nzvimbo ye78,706 m2, ine 13 API zvigadzirwa zvinosanganisira Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, uye 11, gadziriro yekugadzira oral poda, mitsara yekugadzira oral. , premix, bolus, mishonga yezvipembenene nemishonga inouraya utachiona, ects.Veyong inopa APIs, anopfuura zana ega- label gadziriro, uye OEM & ODM sevhisi.
Veyong inokoshesa zvikuru manejimendi eEHS(Environment, Health & Safety) system, uye yakawana ISO14001 uye OHSAS18001 zvitupa.Veyong yakanyorwa mumabhizinesi ari kusimukira maindasitiri muHebei Province uye inogona kuve nechokwadi chekuenderera mberi kwezvigadzirwa.
Veyong yakamisa hurongwa hwekutonga kwemhando yakakwana, yakawana chitupa cheISO9001, chitupa cheChina GMP, chitupa cheAustralia APVMA GMP, chitupa cheEthiopia GMP, chitupa cheIvermectin CEP, uye yakapasa ongororo yeUS FDA.Veyong ine timu yehunyanzvi yekunyoresa, kutengesa uye tekinoroji sevhisi, kambani yedu yakawana kuvimba nerutsigiro kubva kune akawanda vatengi nemhando yepamusoro yechigadzirwa, yepamusoro-yemhando yepamusoro-yekutanga kutengesa uye mushure mekutengesa sevhisi, yakakomba uye yesainzi manejimendi.Veyong yaita kushandira pamwe kwenguva refu nemabhizinesi mazhinji anozivikanwa pasi rose emishonga yemhuka ane zvigadzirwa zvinotengeswa kuEurope, South America, Middle East, Africa, Asia, etc. kupfuura nyika makumi matanhatu nematunhu.
