Tildipirosin
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Tildipirosin
Tildipirosin rudzi rutsva rwemhando yeSemi-Synthetic 16-Memaboler Ring Macrodide Antibiotic Antibiotic yemhuka, iyo inobviswa tylosin.
Pharmacological chiito
Iyo antibacterial mhedzisiro ye tildipirosin yakafanana neye tylosin, uye ine yakasimba inhibitory mune gram-yakanaka mabhakitiriya uye mamwe mabhakitiriya asina kunaka. Iyo antibacterial mechanism ye tildipirosin yakafanana neiyo ye macrolicide. Inogona kusanganisa iyo 50s Subunit yeiyo Ribvu yehutachiona hwehutachiona kuti udzivise synthesis yeRibopretein yePeptide maketins, nekudaro inokanganisa iyo synthesis yemapuroteni ehutachiona. Kubatanidzwa kwezvinhu zviviri zvipuka zvepaperi
Nekuti Tediroxine ine 3 Basic amino mapoka, inogona kuumba akasiyana mafomu ekubhadhara akasiyana pasi pemamiriro akasiyana. Huwandu hwekuvapa chinhu chakakosha kuparadza solubility lipsial lipids uye vapinda mumabhora ekunze eGram-isina kunaka bactiisi, saka chiitiko cheBactiontatic yeTiltipirosin muVitro inokanganiswa zvikuru naP. Pasi pemamiriro ezvinyorwa, boka reAmbino rinogadziriswa, rikonzera kuderera kwechiitiko cheTediroxine yeTediroxine, ichiri pasi peAlkaline mamiriro, ine simba rakasimba reAntibacterial.
Maclitides Inhibit Chinyorwa cheCominflamitory Cytotokines, phospholipase chiitiko, uye leukotrie kusunungurwa, uye kuve nemanyowa anondikurira muMacrophils uye neutrophils. TEDIROXINE inoderedza mwero wekuzvimba zvinogadzirwa panguva yekuita dzimwe nzira dzekuzvidza kana kushushikana.
Antibacterial spectrum
Tilipishingin inoshanda patsikisi bactia inokonzeresa zvePathgenic mumatanda nemombe (borcohiphillus multopneumonia, manniphilus prasuis Tilmicosin, uye chiitiko cheAntibacterial needstinal Escherichia coli yaive nani pane tylosin uye tlmicosin. Izvo zvakare zvine hanya nedzimwe mycoplasma starins, spirochesma, brucelyla, etcceces yakaratidza tediroxine pane farorfenicaction on florfenicaction Tildipirosin ndeye bacterididal kune mamwe mabhakitiriya (senge haemophilus parasuis pleulopneumoniae), kunyange ichinyanya kuwanzoitika kune mamwe mabhakitiriya (senge pasturella Multocida). Kwematumbu mudumbu wePP kukosha (kubva 7.3 kusvika 6.7), mic yeTiliprosin yakawedzera, escherichia coli inogona kuwedzera kubva ku2 ~ 8ug / m kusvika 64 ~ 256ug / ml. Naizvozvo, mhedzisiro yePH inoshanduka mu vivo inofanirwa kutariswa kana ichiitisa iyo muVivo musi wetibacterial bvunzo ye tilipirosin. Uye zvakare, iyo mic yei tilipirosin inopesana neyakajairika marara e pasteurella Multoecda yaive 0.5g / ml muSerum, iyo yaive 0.25 Times yakaderera pane iyo vitro, iyo inogona kuve yakanangana ne serum.
Enterococccus-straptococccus mumombe dzemombe dzinodzivirira zvakanyanya kuTediroxine. Tildipirosin haina hanya naPasteurella Multocida uye Mannheimia Haemolyticus kutakura mutambi majini. Saizvozvo, genetically yakazvitakura madhiri eM. Bovis ari kupokana neMacrolide mishonga inorwisa mabhakitiriya kusanganisira tildipirosin. Mamwe mauto eHasophilus Parasuis akawanikwa akawanikwa achizoita zvechisikirwo kuTediroxine. Mycoplasma Bovis inogona kukurumidza kuwana kupokana neTilishishosin, asi nekuda kwekukura zvishoma kweMycoplasma, muVitro Dishment Kuedza Kunogona Kunonoka Kurapwa. Zvidzidzo zvakaratidza kuti Domain II (NUCLETIZE 748) uye domain v (MUDZIMAI MUNUCLICERISS 2059 uye 2060) inosanganiswa nekuwedzera kuramba macrodides. Naizvozvo, kusanzwisisika kweM. Bovis kune macrolide zvinodhaka kunogona kukurumidza kuwanikwa nekuongororwa kwemanyorerwe nekuongororwa kweiyi mutation.
Zvemukati
≥ 98%
Kutaurwa
Kambani Standard
HEBEI VEYONG PHEMACALUTICAL CO, LTD, yakagadzwa muna 2002, iri muShijizhuang Guta, HEBEI Province, China, padivi peguta guru beijing. Iye iguru rakakura Sezvo provencial technical centre, veyong yakaisa iyo yeRidheni yeR & D yechiitiko chevateridzi, uye ndiyo inozivikanwa yerudzi runyorwa rwehunyanzvi hwenostical Veyong ine zvigadziko zviviri zvekugadzira: Shijizhuang uye yeiyo iyo Shijizhuang base inovhara maHydrochlar, Bolus, mishonga yechipfuva uye disinfectant, ects. Veyong inopa apis, inodarika 100 yekugadzirira, uye OEM & ODM Service.
Veyong anotsvaga kukosha kukuru kune manejimendi eEHS (nharaunda, hutano & kuchengetedza) system, uye yakawana iyo iso1001 uye OHSAS18001 zvitupa. Veyong yakanyorwa mumarongero emunguva inobuda mumabhizimusi muHebeid muBedi Province uye anogona kuve nechokwadi chekuisa kugovera kwezvigadzirwa.
Veyong vakatanga iyo yakazara mhando yemhando system, yakawana iyo SOO9001 Setifiketi, China GRMS Setifiketi, Australia Apm Setififiketi, Ivermectin Cepictate, uye yadarika US FDA kuongorora. Veyong vane nyanzvi yekudzikama, kutengesa uye technical service, yedu tsigiro kubva kune vatengi vakawanda neiyo yechigadzirwa chechigadzirwa, yakakwirira-nzira yekutengesa uye mushure mekutengesa-mutengesi, manejimendi uye akakosha uye ane ruzivo uye manejimendi. Veyong vakawana nguva refu kushandira pamwe nevazhinji vanozivikanwa emaperembudzi ezvivakwa nezvigadzirwa zvinotumirwa kuEurope, South America, Middle East, Africa, etc., etc. dzinopfuura nyika makumi matanhatu nematunhu.
